DeltaVision Elite System fluorescence microscope is a wide-field imaging system for 3D cell culture imaging. It is equipped with an environmental chamber for controlling temperature and CO2 for live cell imaging.
Functional validation of endogenously HaloTagged telomeric protein TPP1 in U2OS cells. Image courtesy of Dr. Tomas Janovic, Dr. Jens Schmidt’s Lab.
U2OS cells that were endogenously edited with a HaloTag at the Atg9 locus are shown. The recruitment of Atg9 (purple) to 6x Ubiqiutin (green) aggregates and the ubiquitin interacting protein P62 (blue) is investigated. The image was acquired with the DeltaVision microscope. Image courtesy of Dr. David Broadbent, Dr. Jens Schmidt’s Lab.